听力与言语-语言病理学

行为科学

医学伦理学

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  • Pitfalls in the clustering of neuroimage data and improvements by global optimization strategies.

    abstract::In this paper, we examined three vector quantization (VQ) methods used for the unsupervised classification (clustering) of functional magnetic resonance imaging (fMRI) data. Classification means that each brain volume element (voxel), according to a given scanning raster, was assigned to one group of voxels based on s...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2001.0792

    authors: Möller U,Ligges M,Grünling C,Georgiewa P,Kaiser WA,Witte H,Blanz B

    更新日期:2001-07-01 00:00:00

  • Working memory for location and time: activity in prefrontal area 46 relates to selection rather than maintenance in memory.

    abstract::The role of the dorsal prefrontal cortex in working memory remains controversial. Influential proposals include a role in the maintenance of domain-specific information, and the processes of executive functions on remembered information. We used event-related functional magnetic resonance imaging to demonstrate a func...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2001.0784

    authors: Rowe JB,Passingham RE

    更新日期:2001-07-01 00:00:00

  • Parallel neural responses in amygdala subregions and sensory cortex during implicit fear conditioning.

    abstract::We used event-related fMRI to measure neural activity in volunteer subjects during acquisition of an implicit association between a visual conditioned stimulus (CS+) (angry face) and an auditory unconditioned stimulus (UCS) (aversive, loud noise). Three distinct functional regions were identified within left amygdala:...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0721

    authors: Morris JS,Buchel C,Dolan RJ

    更新日期:2001-06-01 00:00:00

  • Arm training induced brain plasticity in stroke studied with serial positron emission tomography.

    abstract::We used serial positron emission tomography (PET) to study training-induced brain plasticity after severe hemiparetic stroke. Ten patients were randomized to either task-oriented arm training or to a control group and scanned before and after 22.6 +/- 1.6 days of treatment using passive movements as an activation para...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1006/nimg.2001.0757

    authors: Nelles G,Jentzen W,Jueptner M,Müller S,Diener HC

    更新日期:2001-06-01 00:00:00

  • The neural system underlying Chinese logograph reading.

    abstract::Written Chinese as logographic script differs notably from alphabets such as English in visual form, orthography, phonology, and semantics. Thus, research on the Chinese language is important to advance our understanding of the universality and particularity of the organization of language systems in the brain. In thi...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2001.0749

    authors: Tan LH,Liu HL,Perfetti CA,Spinks JA,Fox PT,Gao JH

    更新日期:2001-05-01 00:00:00

  • Cortical responses to single mechanoreceptive afferent microstimulation revealed with fMRI.

    abstract::The technique of intraneural microneurography/microstimulation has been used extensively to study contributions of single, physiologically characterized mechanoreceptive afferents (MRAs) to properties of somatosensory experience in awake human subjects. Its power as a tool for sensory neurophysiology can be greatly en...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0723

    authors: Trulsson M,Francis ST,Kelly EF,Westling G,Bowtell R,McGlone F

    更新日期:2001-04-01 00:00:00

  • Ranking fMRI time courses by minimum spanning trees: assessing coactivation in fMRI.

    abstract::In fMRI, time courses with similar temporal "activation" patterns may belong to different brain regions (i.e., these regions are functionally connected, coactivated). A group of time courses (TCs) corresponding to a particular type of temporal activation pattern should be maximally self-consistent (homogeneous). We de...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0729

    authors: Baumgartner R,Somorjai R,Summers R,Richter W

    更新日期:2001-04-01 00:00:00

  • Signal source separation in the analysis of neural activity in brain.

    abstract::This research examines the spatial and temporal characteristics of the responses to stimulation of the barrel cortex in anesthetized rats using optical imaging with particular emphasis on methods of analysis which reduce the effects of low-frequency oscillations on localization of the activated cortical region. Image ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0705

    authors: Zheng Y,Johnston D,Berwick J,Mayhew J

    更新日期:2001-03-01 00:00:00

  • Representation of the ear in human primary somatosensory cortex.

    abstract::We studied 13 healthy subjects with a multichannel magnetoencephalography (MEG) system to investigate the somatotopic representation of the ear in the primary somatosensory cortex (SI). We stimulated three parts of the left ear: the helix, the lobulus, and the tragus. The somatosensory-evoked magnetic fields (SEFs) we...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0695

    authors: Nihashi T,Kakigi R,Kawakami O,Hoshiyama M,Itomi K,Nakanishi H,Kajita Y,Inao S,Yoshida J

    更新日期:2001-02-01 00:00:00

  • The effect of medial frontal and posterior parietal demyelinating lesions on stroop interference.

    abstract::Functional imaging has consistently shown that attention-related areas of medial frontal and posterior parietal cortices are active during the attentional conflict induced by color naming in the presence of distracting words (Stroop task). Such studies, however, have provided few details of the correlational nature be...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.2000.0662

    authors: Pujol J,Vendrell P,Deus J,Junqué C,Bello J,Martí-Vilalta JL,Capdevila A

    更新日期:2001-01-01 00:00:00

  • Accuracy and sensitivity of detection of activation foci in the brain via statistical parametric mapping: a study using a PET simulator.

    abstract::Statistical parametric mapping (SPM) is currently the most widely used method for analysis of functional activation images. This paper reports a quantitative evaluation of the sensitivity and accuracy of SPM, using a realistic simulator of PET image formation, which accounted for the main physical processes involved i...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1006/nimg.2000.0655

    authors: Davatzikos C,Li HH,Herskovits E,Resnick SM

    更新日期:2001-01-01 00:00:00

  • Specific versus nonspecific brain activity in a parametric N-back task.

    abstract::In this study functional magnetic resonance imaging (fMRI) was used to examine cerebral activity patterns in relation to increasing mental load of a working memory task. Aim of the experiment was to distinguish nonspecific task-related processes from specific workload processes analytically. Twelve healthy volunteers ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0645

    authors: Jansma JM,Ramsey NF,Coppola R,Kahn RS

    更新日期:2000-12-01 00:00:00

  • The effect of switching between sequential and repetitive movements on cortical activation.

    abstract::We used whole-head functional magnetic resonance imaging (fMRI) to investigate the effect of switching between different sequential and repetitive movements in the context of conditional and fixed tasks. Four different movement tasks were applied: (1) unpredictable switching between two movement sequences comprising s...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0626

    authors: Jäncke L,Himmelbach M,Shah NJ,Zilles K

    更新日期:2000-11-01 00:00:00

  • Dissociating prefrontal and parietal cortex activation during arithmetic processing.

    abstract::Lesion and brain-imaging studies have implicated the prefrontal and parietal cortices in arithmetic processing, but do not exclude the possibility that these brain areas are also involved in nonarithmetic operations. In the present study, we used functional magnetic resonance imaging to explore which brain areas contr...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0613

    authors: Menon V,Rivera SM,White CD,Glover GH,Reiss AL

    更新日期:2000-10-01 00:00:00

  • Nonlinear responses in fMRI: the Balloon model, Volterra kernels, and other hemodynamics.

    abstract::There is a growing appreciation of the importance of nonlinearities in evoked responses in fMRI, particularly with the advent of event-related fMRI. These nonlinearities are commonly expressed as interactions among stimuli that can lead to the suppression and increased latency of responses to a stimulus that are incur...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0630

    authors: Friston KJ,Mechelli A,Turner R,Price CJ

    更新日期:2000-10-01 00:00:00

  • Neural correlates of episodic retrieval success.

    abstract::Episodic memory retrieval involves multiple component processes, including those that occur when information is correctly remembered (retrieval success). The present study employed rapid-presentation event-related functional MRI that allowed different trial types with short intertrial intervals to be sorted such that ...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.2000.0614

    authors: Konishi S,Wheeler ME,Donaldson DI,Buckner RL

    更新日期:2000-09-01 00:00:00

  • Movement-related electroencephalographic reactivity in Alzheimer disease.

    abstract::Event-related desynchronization/synchronization (ERD/ERS) of alpha and beta electroencephalographic (EEG) rhythms was investigated in normal subjects and mild Alzheimer Disease patients (AD), performing unilateral right finger movements (about 10 s intermovement interval). Electroencephalographic data were sampled bas...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.2000.0602

    authors: Babiloni C,Babiloni F,Carducci F,Cincotti F,Del Percio C,De Pino G,Maestrini S,Priori A,Tisei P,Zanetti O,Rossini PM

    更新日期:2000-08-01 00:00:00

  • The representation of shape in the context of visual object categorization tasks.

    abstract::To investigate the role of human fusiform gyrus in shape processing, we determined the effect of shape degradation on BOLD contrast in this region with fMRI during three tasks requiring subjects to determine either whether two successively presented nonsense shapes had the same global orientation (OR task); whether tw...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0598

    authors: Op de Beeck H,Béatse E,Wagemans J,Sunaert S,Van Hecke P

    更新日期:2000-07-01 00:00:00

  • Attention to speed of motion, speed discrimination, and task difficulty: an fMRI study.

    abstract::We studied the functional neuroanatomy of attention to speed of motion using functional magnetic resonance imaging in eight healthy subjects, who performed a speed discrimination (SID) task using a random textured pattern moving at a reference speed of 6 deg/s. During the control condition (DIM), with retinal stimulat...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0587

    authors: Sunaert S,Van Hecke P,Marchal G,Orban GA

    更新日期:2000-06-01 00:00:00

  • Extrastriatal mean regional uptake of fluorine-18-FDOPA in the normal aged brain--an approach using MRI-aided spatial normalization.

    abstract::The aim of this study was to define the mean regional 6-[(18)F]fluoro-l-dopa (FDOPA) uptake rate constant (K(i)) values in the striatal and extrastriatal regions of the brain of normal subjects using magnetic resonance imaging (MRI)-aided spatial normalization of the FDOPA K(i) image and using automatic region of inte...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0584

    authors: Nagano AS,Ito K,Kato T,Arahata Y,Kachi T,Hatano K,Kawasumi Y,Nakamura A,Yamada T,Abe Y,Ishigaki T

    更新日期:2000-06-01 00:00:00

  • Evidence for a refractory period in the hemodynamic response to visual stimuli as measured by MRI.

    abstract::We investigated the effects of paired presentations of visual stimuli upon the evoked hemodynamic response of visual cortex measured by magnetic resonance imaging (MRI). Stimuli were identical 500-ms high-contrast checkerboard patterns, presented singly or with an interpair interval (IPI) of 1, 2, 4, or 6 s (onset-to-...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0553

    authors: Huettel SA,McCarthy G

    更新日期:2000-05-01 00:00:00

  • Visualization of subthalamic nuclei with cortex attenuated inversion recovery MR imaging.

    abstract::There is a significant amount of interest in studying the thalamus because of its central location in the brain and its role as a gatekeeper to higher centers of cognition. Imaging and measuring of the individual subnuclei of the thalamus has proven extremely difficult in MR because of the contrast-to-noise (CNR) of t...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2000.0552

    authors: Magnotta VA,Gold S,Andreasen NC,Ehrhardt JC,Yuh WT

    更新日期:2000-04-01 00:00:00

  • The relationship between fMRI activation and cerebral atrophy: comparison of normal aging and alzheimer disease.

    abstract::Functional MRI has recently been used to examine activation associated with aging and dementia, yet little is known regarding the effect of cerebral atrophy on fMRI signal. The purpose of this study was to examine the relationship between measures of global and regionally specific atrophy and fMRI activation in normal...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0530

    authors: Johnson SC,Saykin AJ,Baxter LC,Flashman LA,Santulli RB,McAllister TW,Mamourian AC

    更新日期:2000-03-01 00:00:00

  • Overt verbal responding during fMRI scanning: empirical investigations of problems and potential solutions.

    abstract::This paper presents a pair of studies designed to empirically explore the severity of potential artifacts associated with overt verbal responding during fMRI scanning and to examine several different solutions to these artifacts. In Study One, we compared susceptibility artifacts, signal-to-noise ratios, and activatio...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0500

    authors: Barch DM,Sabb FW,Carter CS,Braver TS,Noll DC,Cohen JD

    更新日期:1999-12-01 00:00:00

  • LOFA: software for individualized localization of functional MRI activity.

    abstract::Although PET, SPECT, and fMRI studies have led to significant advances in functional mapping of the human brain, precise localization and quantification of activity in individual brains require additional procedures. Difficulties to be addressed by a localization strategy are: resolution of individual anatomic differe...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0511

    authors: Gökçay D,Mohr CM,Crosson B,Leonard CM,Bobholz JA

    更新日期:1999-12-01 00:00:00

  • Comparison of filtering methods for fMRI datasets.

    abstract::When studying complex cognitive tasks using functional magnetic resonance imaging (fMRI) one often encounters weak signal responses. These weak responses are corrupted by noise and artifacts of various sources. Preprocessing of the raw data before the application of test statistics helps to extract the signal and can ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0490

    authors: Kruggel F,von Cramon DY,Descombes X

    更新日期:1999-11-01 00:00:00

  • Event-related fMRI of the auditory cortex.

    abstract::An event-related protocol was designed to permit auditory fMRI studies minimally affected by the echo-planar noise artifact; a long time interval (TR = 10 s) between each cerebral volume acquisition was combined with stroboscopic data acquisition, and event-related curves were reconstructed with a 1-s resolution. The ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0480

    authors: Belin P,Zatorre RJ,Hoge R,Evans AC,Pike B

    更新日期:1999-10-01 00:00:00

  • Three-dimensional MRI atlas of the human cerebellum in proportional stereotaxic space.

    abstract::We have prepared an atlas of the human cerebellum using high-resolution magnetic resonance-derived images warped into the proportional stereotaxic space of Talairach and Tournoux. Software that permits simultaneous visualization of the three cardinal planes facilitated the identification of the cerebellar fissures and...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1999.0459

    authors: Schmahmann JD,Doyon J,McDonald D,Holmes C,Lavoie K,Hurwitz AS,Kabani N,Toga A,Evans A,Petrides M

    更新日期:1999-09-01 00:00:00

  • Three distinct ventral occipitotemporal regions for reading and object naming.

    abstract::This study investigates word and object processing during naming and viewing tasks and identifies three distinct regions in the left ventral occipitotemporal cortex. Irrespective of task, words and objects (relative to meaningless visual controls) activated the medial surface of the left anterior fusiform gyrus, a reg...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1006/nimg.1999.0450

    authors: Moore CJ,Price CJ

    更新日期:1999-08-01 00:00:00

  • Effective auditory-verbal encoding activates the left prefrontal and the medial temporal lobes: A generalization to illiterate subjects.

    abstract::Recent event-related FMRI studies indicate that the prefrontal (PFC) and the medial temporal lobe (MTL) regions are more active during effective encoding than during ineffective encoding. The within-subject design and the use of well-educated young college students in these studies makes it important to replicate thes...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.1999.0446

    authors: Petersson KM,Reis A,Castro-Caldas A,Ingvar M

    更新日期:1999-07-01 00:00:00

  • A functional anatomy of anticipatory anxiety.

    abstract::Anticipatory anxiety is a complex combination of a future-oriented cognitive state, negative affect, and autonomic arousal. A dual-task paradigm of anticipation of electric shocks and a motor-learning task was used to examine the changes in neural patterns of activation associated with modulation of the cognitive stat...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.1999.0407

    authors: Chua P,Krams M,Toni I,Passingham R,Dolan R

    更新日期:1999-06-01 00:00:00

  • Speed-dependent responses in V5: A replication study.

    abstract::In a previous paper, we used fMRI to examine motion-sensitive responses in human area V5 as a function of stimulus speed. As predicted by electrophysiological findings, we observed optimal responses at intermediate speeds of around 7 to 30 degrees /s. These results revealed a nonlinear (inverted "U") dependency on spe...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.1999.0432

    authors: Chawla D,Buechel C,Edwards R,Howseman A,Josephs O,Ashburner J,Friston KJ

    更新日期:1999-05-01 00:00:00

  • Deconvolution of impulse response in event-related BOLD fMRI.

    abstract::The temporal characteristics of the BOLD response in sensorimotor and auditory cortices were measured in subjects performing finger tapping while listening to metronome pacing tones. A repeated trial paradigm was used with stimulus durations of 167 ms to 16 s and intertrial times of 30 s. Both cortical systems were fo...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.1998.0419

    authors: Glover GH

    更新日期:1999-04-01 00:00:00

  • On clustering fMRI time series.

    abstract::Analysis of fMRI time series is often performed by extracting one or more parameters for the individual voxels. Methods based, e.g., on various statistical tests are then used to yield parameters corresponding to probability of activation or activation strength. However, these methods do not indicate whether sets of v...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0391

    authors: Goutte C,Toft P,Rostrup E,Nielsen F,Hansen LK

    更新日期:1999-03-01 00:00:00

  • Load-dependent roles of frontal brain regions in the maintenance of working memory.

    abstract::Brain imaging studies have suggested a critical role for prefrontal cortex in working memory (WM) tasks that require both maintainenance and manipulation of information over time in delayed-response WM tasks. In the present study, functional magnetic resonance imaging (fMRI) was used to examine whether prefrontal area...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0404

    authors: Rypma B,Prabhakaran V,Desmond JE,Glover GH,Gabrieli JD

    更新日期:1999-02-01 00:00:00

  • Functional neuroanatomy of semantic memory: recognition of semantic associations.

    abstract::In an effort to examine the functional neuroanatomy of semantic memory, we studied the relative cerebral blood flow of eight healthy young subjects using 15O-water positron emission tomography (PET). Relative to a visual baseline control condition, each of four visual matching-to-sample tasks activated components of t...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0386

    authors: Ricci PT,Zelkowicz BJ,Nebes RD,Meltzer CC,Mintun MA,Becker JT

    更新日期:1999-01-01 00:00:00

  • Biophysical linkage between MRI and EEG coherence in closed head injury.

    abstract::Using conventional MRI procedures, nuclear magnetic resonance (NMR) of brain water proton (1H) T2 relaxation times and EEG coherence were obtained from two independent groups of closed head injured (CHI) patients and a group of normal control subjects. Statistically significant intercorrelations were observed between ...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1006/nimg.1998.0365

    authors: Thatcher RW,Biver C,McAlaster R,Salazar A

    更新日期:1998-11-01 00:00:00

  • Neural correlates of memory retrieval during recognition memory and cued recall.

    abstract::Regional brain activity, measured by H215O PET, was investigated during recognition memory and word-stem cued recall of words in order to compare the neural correlates of two components of memory retrieval-effort and success-as a function of task. For each task there was a baseline and two retrieval conditions. In one...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0363

    authors: Rugg MD,Fletcher PC,Allan K,Frith CD,Frackowiak RS,Dolan RJ

    更新日期:1998-10-01 00:00:00

  • Differential activation of right superior parietal cortex and intraparietal sulcus by spatial and nonspatial attention.

    abstract::Neuropsychological and functional neuroimaging studies have implicated the right posterior parietal cortex (PPC) in human spatial attention. We tested the hypothesis that this area is also involved in nonspatial aspects of attention and working memory using positron emission tomography in healthy volunteers. In an ini...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0354

    authors: Coull JT,Frith CD

    更新日期:1998-08-01 00:00:00

  • Uncoupling cognitive workload and prefrontal cortical physiology: a PET rCBF study.

    abstract::Working memory is a fundamental cognitive building block involved in the short-term maintenance and transformation of information. In neuropsychological studies, working memory has been shown to be of limited capacity; however, the neurophysiological concomitants of this capacity limitation have not been explored. In ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.1998.0338

    authors: Goldberg TE,Berman KF,Fleming K,Ostrem J,Van Horn JD,Esposito G,Mattay VS,Gold JM,Weinberger DR

    更新日期:1998-05-01 00:00:00

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