解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In this paper, we examined three vector quantization (VQ) methods used for the unsupervised classification (clustering) of functional magnetic resonance imaging (fMRI) data. Classification means that each brain volume element (voxel), according to a given scanning raster, was assigned to one group of voxels based on s...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0792
更新日期:2001-07-01 00:00:00
abstract::The role of the dorsal prefrontal cortex in working memory remains controversial. Influential proposals include a role in the maintenance of domain-specific information, and the processes of executive functions on remembered information. We used event-related functional magnetic resonance imaging to demonstrate a func...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0784
更新日期:2001-07-01 00:00:00
abstract::We used event-related fMRI to measure neural activity in volunteer subjects during acquisition of an implicit association between a visual conditioned stimulus (CS+) (angry face) and an auditory unconditioned stimulus (UCS) (aversive, loud noise). Three distinct functional regions were identified within left amygdala:...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0721
更新日期:2001-06-01 00:00:00
abstract::We used serial positron emission tomography (PET) to study training-induced brain plasticity after severe hemiparetic stroke. Ten patients were randomized to either task-oriented arm training or to a control group and scanned before and after 22.6 +/- 1.6 days of treatment using passive movements as an activation para...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1006/nimg.2001.0757
更新日期:2001-06-01 00:00:00
abstract::Written Chinese as logographic script differs notably from alphabets such as English in visual form, orthography, phonology, and semantics. Thus, research on the Chinese language is important to advance our understanding of the universality and particularity of the organization of language systems in the brain. In thi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0749
更新日期:2001-05-01 00:00:00
abstract::The technique of intraneural microneurography/microstimulation has been used extensively to study contributions of single, physiologically characterized mechanoreceptive afferents (MRAs) to properties of somatosensory experience in awake human subjects. Its power as a tool for sensory neurophysiology can be greatly en...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0723
更新日期:2001-04-01 00:00:00
abstract::In fMRI, time courses with similar temporal "activation" patterns may belong to different brain regions (i.e., these regions are functionally connected, coactivated). A group of time courses (TCs) corresponding to a particular type of temporal activation pattern should be maximally self-consistent (homogeneous). We de...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0729
更新日期:2001-04-01 00:00:00
abstract::This research examines the spatial and temporal characteristics of the responses to stimulation of the barrel cortex in anesthetized rats using optical imaging with particular emphasis on methods of analysis which reduce the effects of low-frequency oscillations on localization of the activated cortical region. Image ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0705
更新日期:2001-03-01 00:00:00
abstract::We studied 13 healthy subjects with a multichannel magnetoencephalography (MEG) system to investigate the somatotopic representation of the ear in the primary somatosensory cortex (SI). We stimulated three parts of the left ear: the helix, the lobulus, and the tragus. The somatosensory-evoked magnetic fields (SEFs) we...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0695
更新日期:2001-02-01 00:00:00
abstract::Functional imaging has consistently shown that attention-related areas of medial frontal and posterior parietal cortices are active during the attentional conflict induced by color naming in the presence of distracting words (Stroop task). Such studies, however, have provided few details of the correlational nature be...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2000.0662
更新日期:2001-01-01 00:00:00
abstract::Statistical parametric mapping (SPM) is currently the most widely used method for analysis of functional activation images. This paper reports a quantitative evaluation of the sensitivity and accuracy of SPM, using a realistic simulator of PET image formation, which accounted for the main physical processes involved i...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1006/nimg.2000.0655
更新日期:2001-01-01 00:00:00
abstract::In this study functional magnetic resonance imaging (fMRI) was used to examine cerebral activity patterns in relation to increasing mental load of a working memory task. Aim of the experiment was to distinguish nonspecific task-related processes from specific workload processes analytically. Twelve healthy volunteers ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0645
更新日期:2000-12-01 00:00:00
abstract::We used whole-head functional magnetic resonance imaging (fMRI) to investigate the effect of switching between different sequential and repetitive movements in the context of conditional and fixed tasks. Four different movement tasks were applied: (1) unpredictable switching between two movement sequences comprising s...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0626
更新日期:2000-11-01 00:00:00
abstract::Lesion and brain-imaging studies have implicated the prefrontal and parietal cortices in arithmetic processing, but do not exclude the possibility that these brain areas are also involved in nonarithmetic operations. In the present study, we used functional magnetic resonance imaging to explore which brain areas contr...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0613
更新日期:2000-10-01 00:00:00
abstract::There is a growing appreciation of the importance of nonlinearities in evoked responses in fMRI, particularly with the advent of event-related fMRI. These nonlinearities are commonly expressed as interactions among stimuli that can lead to the suppression and increased latency of responses to a stimulus that are incur...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0630
更新日期:2000-10-01 00:00:00
abstract::Episodic memory retrieval involves multiple component processes, including those that occur when information is correctly remembered (retrieval success). The present study employed rapid-presentation event-related functional MRI that allowed different trial types with short intertrial intervals to be sorted such that ...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2000.0614
更新日期:2000-09-01 00:00:00
abstract::Event-related desynchronization/synchronization (ERD/ERS) of alpha and beta electroencephalographic (EEG) rhythms was investigated in normal subjects and mild Alzheimer Disease patients (AD), performing unilateral right finger movements (about 10 s intermovement interval). Electroencephalographic data were sampled bas...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2000.0602
更新日期:2000-08-01 00:00:00
abstract::To investigate the role of human fusiform gyrus in shape processing, we determined the effect of shape degradation on BOLD contrast in this region with fMRI during three tasks requiring subjects to determine either whether two successively presented nonsense shapes had the same global orientation (OR task); whether tw...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0598
更新日期:2000-07-01 00:00:00
abstract::We studied the functional neuroanatomy of attention to speed of motion using functional magnetic resonance imaging in eight healthy subjects, who performed a speed discrimination (SID) task using a random textured pattern moving at a reference speed of 6 deg/s. During the control condition (DIM), with retinal stimulat...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0587
更新日期:2000-06-01 00:00:00
abstract::The aim of this study was to define the mean regional 6-[(18)F]fluoro-l-dopa (FDOPA) uptake rate constant (K(i)) values in the striatal and extrastriatal regions of the brain of normal subjects using magnetic resonance imaging (MRI)-aided spatial normalization of the FDOPA K(i) image and using automatic region of inte...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0584
更新日期:2000-06-01 00:00:00
abstract::We investigated the effects of paired presentations of visual stimuli upon the evoked hemodynamic response of visual cortex measured by magnetic resonance imaging (MRI). Stimuli were identical 500-ms high-contrast checkerboard patterns, presented singly or with an interpair interval (IPI) of 1, 2, 4, or 6 s (onset-to-...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0553
更新日期:2000-05-01 00:00:00
abstract::There is a significant amount of interest in studying the thalamus because of its central location in the brain and its role as a gatekeeper to higher centers of cognition. Imaging and measuring of the individual subnuclei of the thalamus has proven extremely difficult in MR because of the contrast-to-noise (CNR) of t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0552
更新日期:2000-04-01 00:00:00
abstract::Functional MRI has recently been used to examine activation associated with aging and dementia, yet little is known regarding the effect of cerebral atrophy on fMRI signal. The purpose of this study was to examine the relationship between measures of global and regionally specific atrophy and fMRI activation in normal...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0530
更新日期:2000-03-01 00:00:00
abstract::This paper presents a pair of studies designed to empirically explore the severity of potential artifacts associated with overt verbal responding during fMRI scanning and to examine several different solutions to these artifacts. In Study One, we compared susceptibility artifacts, signal-to-noise ratios, and activatio...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0500
更新日期:1999-12-01 00:00:00
abstract::Although PET, SPECT, and fMRI studies have led to significant advances in functional mapping of the human brain, precise localization and quantification of activity in individual brains require additional procedures. Difficulties to be addressed by a localization strategy are: resolution of individual anatomic differe...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0511
更新日期:1999-12-01 00:00:00
abstract::When studying complex cognitive tasks using functional magnetic resonance imaging (fMRI) one often encounters weak signal responses. These weak responses are corrupted by noise and artifacts of various sources. Preprocessing of the raw data before the application of test statistics helps to extract the signal and can ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0490
更新日期:1999-11-01 00:00:00
abstract::An event-related protocol was designed to permit auditory fMRI studies minimally affected by the echo-planar noise artifact; a long time interval (TR = 10 s) between each cerebral volume acquisition was combined with stroboscopic data acquisition, and event-related curves were reconstructed with a 1-s resolution. The ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0480
更新日期:1999-10-01 00:00:00
abstract::We have prepared an atlas of the human cerebellum using high-resolution magnetic resonance-derived images warped into the proportional stereotaxic space of Talairach and Tournoux. Software that permits simultaneous visualization of the three cardinal planes facilitated the identification of the cerebellar fissures and...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0459
更新日期:1999-09-01 00:00:00
abstract::This study investigates word and object processing during naming and viewing tasks and identifies three distinct regions in the left ventral occipitotemporal cortex. Irrespective of task, words and objects (relative to meaningless visual controls) activated the medial surface of the left anterior fusiform gyrus, a reg...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1006/nimg.1999.0450
更新日期:1999-08-01 00:00:00
abstract::Recent event-related FMRI studies indicate that the prefrontal (PFC) and the medial temporal lobe (MTL) regions are more active during effective encoding than during ineffective encoding. The within-subject design and the use of well-educated young college students in these studies makes it important to replicate thes...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.1999.0446
更新日期:1999-07-01 00:00:00
abstract::Anticipatory anxiety is a complex combination of a future-oriented cognitive state, negative affect, and autonomic arousal. A dual-task paradigm of anticipation of electric shocks and a motor-learning task was used to examine the changes in neural patterns of activation associated with modulation of the cognitive stat...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.1999.0407
更新日期:1999-06-01 00:00:00
abstract::In a previous paper, we used fMRI to examine motion-sensitive responses in human area V5 as a function of stimulus speed. As predicted by electrophysiological findings, we observed optimal responses at intermediate speeds of around 7 to 30 degrees /s. These results revealed a nonlinear (inverted "U") dependency on spe...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.1999.0432
更新日期:1999-05-01 00:00:00
abstract::The temporal characteristics of the BOLD response in sensorimotor and auditory cortices were measured in subjects performing finger tapping while listening to metronome pacing tones. A repeated trial paradigm was used with stimulus durations of 167 ms to 16 s and intertrial times of 30 s. Both cortical systems were fo...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.1998.0419
更新日期:1999-04-01 00:00:00
abstract::Analysis of fMRI time series is often performed by extracting one or more parameters for the individual voxels. Methods based, e.g., on various statistical tests are then used to yield parameters corresponding to probability of activation or activation strength. However, these methods do not indicate whether sets of v...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0391
更新日期:1999-03-01 00:00:00
abstract::Brain imaging studies have suggested a critical role for prefrontal cortex in working memory (WM) tasks that require both maintainenance and manipulation of information over time in delayed-response WM tasks. In the present study, functional magnetic resonance imaging (fMRI) was used to examine whether prefrontal area...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0404
更新日期:1999-02-01 00:00:00
abstract::In an effort to examine the functional neuroanatomy of semantic memory, we studied the relative cerebral blood flow of eight healthy young subjects using 15O-water positron emission tomography (PET). Relative to a visual baseline control condition, each of four visual matching-to-sample tasks activated components of t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0386
更新日期:1999-01-01 00:00:00
abstract::Using conventional MRI procedures, nuclear magnetic resonance (NMR) of brain water proton (1H) T2 relaxation times and EEG coherence were obtained from two independent groups of closed head injured (CHI) patients and a group of normal control subjects. Statistically significant intercorrelations were observed between ...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.1998.0365
更新日期:1998-11-01 00:00:00
abstract::Regional brain activity, measured by H215O PET, was investigated during recognition memory and word-stem cued recall of words in order to compare the neural correlates of two components of memory retrieval-effort and success-as a function of task. For each task there was a baseline and two retrieval conditions. In one...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0363
更新日期:1998-10-01 00:00:00
abstract::Neuropsychological and functional neuroimaging studies have implicated the right posterior parietal cortex (PPC) in human spatial attention. We tested the hypothesis that this area is also involved in nonspatial aspects of attention and working memory using positron emission tomography in healthy volunteers. In an ini...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0354
更新日期:1998-08-01 00:00:00
abstract::Working memory is a fundamental cognitive building block involved in the short-term maintenance and transformation of information. In neuropsychological studies, working memory has been shown to be of limited capacity; however, the neurophysiological concomitants of this capacity limitation have not been explored. In ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0338
更新日期:1998-05-01 00:00:00